Corneal and other ocular surface applications.
Autologous serum, platelet concentrate and platelet gel are distinct preparations. Product form matters in ocular-surface and vitreoretinal research. Findings for one preparation do not establish ocular suitability or approval for another Plateltex configuration.
Autologous serum and platelet-based preparations have been investigated in severe dry eye, persistent epithelial defects, neurotrophic keratitis and ocular graft-versus-host disease. Growth factors, fibronectin, lysozyme and vitamin A contribute to the biological rationale.
Macular hole studies in the 1990s examined gas tamponade combined with platelet concentrate. Anatomical findings reported in the Cork and Paris references depend on gas, surgical technique and study groups. They are not direct evidence that Plateltex gel is superior to current standard treatment.
Platelet concentration, volume, preparation method and sterility conditions depend on the application. Suitability for ocular use cannot be established merely because a system produces PRP; product instructions and ophthalmological assessment are essential.